Autologous rosette-forming T cells as the responding cells in human autologous mixed-lymphocyte reaction.
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منابع مشابه
Autologous rosette-forming T cells as the responding cells in human autologous mixed-lymphocyte reaction.
Autologous rosette-forming cells (Tar cells) have surface and functional characteristics of post-thymic precursors and among these characteristics there are some that have been identified in the responsive cell of the autologous mixed-lymphocyte reaction (AMLR). We therefore did AMLR with circulating mononuclear cells from normal subjects using as responding cells either total T cells, T cells ...
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Received for publication 15 December 1980 and in revised form 23 March 198
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Isolated human T4+ cells proliferate in the autologous mixed lymphocyte reaction (AMLR), whereas isolated T8+ cells do not. However, in the presence of Interleukin 2 or T4+ cells, the T8+ cells demonstrated substantial proliferation. These studies suggest that T8+ cells recognize signals from autologous non-T cells, but require an additional factor for the subsequent proliferative response. Sin...
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Received for publication 15 December 1980 and in revised form 23 March 198
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ژورنال
عنوان ژورنال: Journal of Clinical Investigation
سال: 1980
ISSN: 0021-9738
DOI: 10.1172/jci109819